N-(3-Aminopropyl)morpholine → HCID 21945929, compound

HRID 1295761Notes

Reaction equation

HRID 1295761 reaction equation
[O:1]=[C:2]1[CH:10]([C:11]2[C:16]3=[C:17]([O:31][CH3:32])[C:18]([C:20]([NH:22][CH2:23][CH2:24][CH2:25][N:26]4[CH:30]=NC=N4)=[O:21])=[CH:19][N:15]3[N:14]=[CH:13][N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3]1.N1(CCCN)C[CH2:37][O:36][CH2:35][CH2:34]1>>[O:1]=[C:2]1[CH:10]([C:11]2[C:16]3=[C:17]([O:31][CH3:32])[C:18]([C:20]([NH:22][CH2:23][CH2:24][CH2:25][N:26]4[CH2:30][CH2:37][O:36][CH2:35][CH2:34]4)=[O:21])=[CH:19][N:15]3[N:14]=[CH:13][N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[NH:3]1

Participants

3

Reactant 2

HCID 61055N-(3-Aminopropyl)morpholineHCID 21945915HCID 21945915, compound

Product 1

HCID 21945929HCID 21945929, compound

Procedure

Compound A of Example 128 was converted to the title compound by the procedure same as that for Example 126 except N-[3-(4-morpholinyl)propylamine was used. MS: (M+H)+=451.

Sources & evidence

ORD record
ord-c977636d6ef3448b86cbb123888b8e4d
Source dataset
uspto-grants-2007_07
Patent number
US07244733B2

Reaction notes

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