HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → Trifluoromethanesulfonic anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Trifluoromethanesulfonate | HCID 2758875 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Trifluoromethanesulfonic anhydride | HCID 67749 | — |
Reaction Steps
Step 2 is a step of conversion of hydroxyl to a trifluoromethanesulfonate (triflate). Compound (B3-c) may be obtained by reaction with trifluoromethanesulfonic anhydride in a solvent such as dichloromethane in the presence of a base such as triethylamine or pyridine, or by reaction with compound (B3-e) in the presence of triethylamine or dimethylaminopyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07244730B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-0762649928824e08abb6335fd6a15e49 |
| Source note | uspto-grants-2007_07 |