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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1296063Generated: October 27, 2026

(6-Hydroxy-benzo[b]thiophen-3-yl)acetic acid methyl ester → HCID 69514708, compound

https://huagongshe.com/reaction/1296063

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(6-Hydroxy-benzo[b]thiophen-3-yl)acetic acid methyl esterHCID 20765985—
ReactantHCID 22504861HCID 22504861—
ProductHCID 69514708HCID 69514708—

Reaction Steps

Compound 69C and Compound 5C were reacted in a manner analogous to Compound 59A to give {6-[2-(3-Fluoro-phenyl)-benzooxazol-5-ylmethoxy]-benzo[b]thiophen-3-yl}-acetic acid methyl ester. This was reacted in a manner analogous to Compound 59 to give the title product. 400 MHz 1H NMR (DMSO-d6) δ ppm 3.7 (s, 2H) 5.3 (s, 2H) 7.1 (dd, J=8.8, 2.4 Hz, 1H) 7.3 (s, 1H) 7.5 (m, 1H) 7.5 (dd, J=8.3, 1.7 Hz, 1H) 7.6 (m, 3H) 7.8 (d, J=8.3 Hz, 1H) 7.9 (m, 2H) 8.0 (dt, J=8.1, 1.1 Hz, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07244763B2
Source datasetuspto-grants-2007_07
ORD IDord-fdf70c7a2c1f4fbb94f44ec573aedbfd
Source noteuspto-grants-2007_07