HRID1296342

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

HCID5957

Adenosine triphosphate

C10H16N5O13P3

HCID135843051

未命名化合物

结构：Nc1nc(=O)c2ncn([C@@H]3O[C@@H]4COP(=O)(O)O[C@H]4[C@H]3O)c2[nH]1

HCID178418274

未命名化合物

PRODUCTS

生成物

结构：Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

HCID6022

Adenosine diphosphate

C10H15N5O10P2

结构：Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

HCID135398619

Guanosine diphosphate

C10H15N5O11P2

PROCEDURE

实验过程

The cGMP present in the sample is then converted to GMP with phosphodiesterase. The GMP is combined with ATP in the presence of guanine monophosphate kinase to yield guanosine-5′-diphosphate (GDP) and ADP.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bb9c97435a1046fa9b95145c4a5dcfd0
来源数据集: uspto-grants-2007_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07247435B2
来源说明: uspto-grants-2007_07

反应 SMILES

[CH:1]1[N:5]([C@@H:6]2[O:10][C@@H:9]3[CH2:11][O:12][P:13]([OH:16])([O:15][C@H:8]3[C@H:7]2[OH:17])=[O:14])[C:4]2[NH:18][C:19]([NH2:23])=[N:20][C:21](=[O:22])[C:3]=2[N:2]=1.[P:24]([O:36][CH2:37][C@H:38]1[O:42][C@@H:41]([N:43]2[C:52]3[N:51]=[CH:50][N:49]=[C:47]([NH2:48])[C:46]=3[N:45]=[CH:44]2)[C@H:40]([OH:53])[C@@H:39]1[OH:54])([O:27][P:28]([O:31]P(O)(O)=O)([OH:30])=[O:29])(=[O:26])[OH:25].P(O)(O)(O)=O.N1C(=O)C2NC=NC=2N=C1N>>[P:13]([O:12][CH2:11][C@H:9]1[O:10][C@@H:6]([N:5]2[C:4]3[N:18]=[C:19]([NH2:23])[NH:20][C:21](=[O:22])[C:3]=3[N:2]=[CH:1]2)[C@H:7]([OH:17])[C@@H:8]1[OH:15])([O:26][P:24]([OH:36])([OH:27])=[O:25])(=[O:14])[OH:16].[P:24]([O:36][CH2:37][C@H:38]1[O:42][C@@H:41]([N:43]2[C:52]3[N:51]=[CH:50][N:49]=[C:47]([NH2:48])[C:46]=3[N:45]=[CH:44]2)[C@H:40]([OH:53])[C@@H:39]1[OH:54])([O:27][P:28]([OH:30])([OH:31])=[O:29])(=[O:25])[OH:26]