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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1296661Generated: October 25, 2026

3-(Phenylmethoxy)benzenemethanol → 2-{[3-(Benzyloxy)Benzyl]Oxy}-6-Chloropyrazine

https://huagongshe.com/reaction/1296661

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Phenylmethoxy)benzenemethanolHCID 74341—
Reactant2,6-DichloropyrazineHCID 78504—
Product2-{[3-(Benzyloxy)Benzyl]Oxy}-6-ChloropyrazineHCID 18186928—

Reaction Steps

The title compound was prepared according to the procedure of example 50, step 1, starting from 3-benzyloxybenzyl alcohol (3.46 g, 16.2 mmol), K-t-BuO (1.69 g, 15.1 mmol) and 2,6-dichloropyrazine (1.97 g, 13.2 mmol). The yield of the title compound was 2.64 g (61%) and was obtained as a semisolid. Anal. (C18H15ClN2O2) C, H, N.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07247633B2
Source datasetuspto-grants-2007_07
ORD IDord-6e319fc23b8242ebbb02d78b53566780
Source noteuspto-grants-2007_07