4-Methoxyphenethyl alcohol → HCID 18186896, compound

HRID 1296665Notes

Reaction equation

HRID 1296665 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([CH2:7][CH2:8][OH:9])=[CH:5][CH:4]=1.[Cl:12][C:13]1[CH:18]=[N:17][CH:16]=[C:15](Cl)[N:14]=1>>[Cl:12][C:13]1[CH:18]=[N:17][CH:16]=[C:15]([O:9][CH2:8][CH2:7][C:6]2[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[N:14]=1

Participants

3

Reactant 2

HCID 697054-Methoxyphenethyl alcoholHCID 785042,6-Dichloropyrazine

Product 1

HCID 18186896HCID 18186896, compound

Procedure

The title compound was prepared according to the procedure of example 50, step 1, starting from 4-methoxyphenethyl alcohol (1.99 g, 13.1 mmol), K-t-BuO (1.34 g, 12.0 mmol) and 2,6-dichloropyrazine (1.56 g, 10.5 mmol). The yield of the title compound was 2.14 g (77%) and was obtained as a white solid. Anal. (C13H13ClN2O2) C, H, N.

Workup

  1. customThe title compound was prepared
  2. customwas obtained as a white solid

Sources & evidence

ORD record
ord-94f009ef37b344b48c0ec1e7fef05333
Source dataset
uspto-grants-2007_07
Patent number
US07247633B2

Reaction notes

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