Piperazine → HCID 9944677, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure of example 50, step 2, starting from 2-chloro-6-[2-(3-methoxyphenyl)ethoxy]pyrazine (1.12 g, 4.23 mmol; obtained according to the procedure of example 50, step 1, starting from 3-methoxyphenethyl alcohol), piperazine (1.06 g, 12.3 mmol) and K2CO3 (0.585 g, 4.23 mmol). The yield of the title compound was 0.91 g (69%) which was obtained as light beige oil. HRMS m/z calcd for C17H22N4O2 (M)+ 314.1743, found 314.1759. Anal. (C17H22N4O2) C, H, N.

Provenance & Evidence