HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-2-(piperidin-1-yl)ethane-1,2-dione → 7-Phenyl-1-azabicyclo[4.2.0]octan-8-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-2-(piperidin-1-yl)ethane-1,2-dione | HCID 10965965 | — |
| Solvent | Water | HCID 962 | — |
| Product | 7-Phenyl-1-azabicyclo[4.2.0]octan-8-one | HCID 12316276 | — |
Reaction Steps
contacting a solution of 1-(phenylglyoxylyl)piperidine arenesulfonylhydrazone in a water immiscible organic solvent with an inorganic base, in the presence of phase transfer catalyst to obtain 7-phenyl-1-azabicyclo[4.2.0]octan-8-one;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07247730B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-c0817e1b17ed4a118cccec7145fd8618 |
| Source note | uspto-grants-2007_07 |