Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1296784Generated: October 30, 2026

Hydrochloric Acid → Methylphenidate

https://huagongshe.com/reaction/1296784

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
Reactant7-Phenyl-1-azabicyclo[4.2.0]octan-8-oneHCID 12316276—
ProductMethylphenidateHCID 4158—

Reaction Steps

reacting the 7-phenyl-1-azabicyclo[4.2.0]octan-8-one obtained in step (i) with a solution of hydrogen chloride in methanol to give methylphenidate;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07247730B2
Source datasetuspto-grants-2007_07
ORD IDord-2f0f3a8f218e46aab45dc7f746ff7ee8
Source noteuspto-grants-2007_07