HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlororesorcinol → 2-(2-Bromo-phenyl)-1-(5-chloro-2,4-dihydroxy-phenyl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlororesorcinol | HCID 1731 | — |
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | 2-Bromophenylacetic acid | HCID 87754 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 2-(2-Bromo-phenyl)-1-(5-chloro-2,4-dihydroxy-phenyl)-ethanone | HCID 58913586 | — |
Reaction Steps
This compounds was synthesised in the same manner as described above. 2-Bromophenylacetic acid (5 g, 23.3 mmol), 4-chlororesorcinol (3.36 g, 23.3 mmol), boron trifloride etherate (20 ml). After standing for two hours a brown precipitate formed (7.4 g, 93.3%); Rf 0.4 hexane/ethyl acetate (70/30). This was shown to be the required product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07247734B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-0f3ad54fa350422abe1e134de6aa54eb |
| Source note | uspto-grants-2007_07 |