Hydrazine hydrate (1:1) → HCID 178489847, compound

Participants

Reaction Steps

This compounds was synthesised in the same manner as described above. 6-Chloro-7-hydroxy-3-(3-methoxy-phenyl)-chromen-4-on (1.0 g, 3.3 mmol), Hydrazine hydrate (8 ml). The quenched reaction was extracted into ethyl acetate, washed (water), dried (MgSO4), and the solvent removed under vacuum to give 4-Chloro-6-[4-(3-methoxy-phenyl)-1H-pyrazol-3-yl]-benzene-1,3-diol as a white solid (0.48 g, 46%); Rf 0.5 ethyl acetate/hexane (80/20)].

Provenance & Evidence