Hydrazine hydrate (1:1) → HCID 178466224, compound

HRID 1296909Notes

Reaction equation

HRID 1296909 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13]1[CH:18]=[CH:17][C:16]([C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([O:25][CH2:26][CH3:27])[CH:20]=3)=[CH:15][CH:14]=1)[C:5]2=O.O.[NH2:30][NH2:31]>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]([C:5]2[C:6]([C:13]3[CH:18]=[CH:17][C:16]([C:19]4[CH:24]=[CH:23][CH:22]=[C:21]([O:25][CH2:26][CH3:27])[CH:20]=4)=[CH:15][CH:14]=3)=[CH:7][NH:31][N:30]=2)[C:9]([OH:8])=[CH:10][C:11]=1[OH:12]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 58913671HCID 58913671, compound

Product 1

HCID 178466224HCID 178466224, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This compounds was synthesised in the same manner as described above. 6-Chloro-3-(3′-ethoxy-biphenyl-4-yl)-7-hydroxy-chromen-4-on (0.2 g, 0.69 mmol), hydrazine hydrate (5 ml), ethanol (10 ml). The quenched solution was extracted into ethyl acetate, washed (water), dried (MgSO4), and the solvent removed under vacuum to give an oil.

Workup

  1. customThis compounds was synthesised in the same manner
  2. extractionThe quenched solution was extracted into ethyl acetate
  3. washwashed (water)
  4. dry with materialdried (MgSO4)
  5. customthe solvent removed under vacuum
  6. customto give an oil

Sources & evidence

ORD record
ord-82f439b054734aa0b59f899cef4bf03d
Source dataset
uspto-grants-2007_07
Patent number
US07247734B2

Reaction notes

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