HCID 86586137, compound → HCID 17825645, compound

Participants

Reaction Steps

2.05 g (3.99 mmol) of 2-cyanoethyl 3-[2-(4-benzyl-[1,4]diazepane-1-carbonyl)-3-oxobutenyl]benzoate and 1.18 g (3.99 mmol) of (3,3-diphenylpropyl)3-aminocrotonate were stirred in 40 ml of 2-propanol at 80° C. overnight. After the concentration under reduced pressure, the product was purified by the silica gel chromatography (chloroform/methanol=100/1) to obtain the title compound.

Provenance & Evidence