HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanimidamide, hydrochloride (1:1) | HCID 10313058 | — |
| Reactant | 2-Amino-5-methoxybenzenesulfonamide | HCID 11252665 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide | HCID 57423887 | — |
Reaction Steps
A suspension of 3.0 g of 2-amino-5-methoxy-benzenesulphonamide is stirred for 1 night at 80° C. in the presence of 1.31 g of formamidine hydrochloride and 2.27 ml of triethylamine in 50 ml of toluene. The toluene is evaporated off in vacuo. The residue is taken up in water and the precipitate is filtered off.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250411B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-f5d30bfff6d74d95a7625a7a8922fcdd |
| Source note | uspto-grants-2007_07 |