Piperazine → HCID 19370261, compound

HRID 129730Notes

Reaction equation

HRID 129730 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([O:15][CH2:16][CH2:17]Cl)[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.[NH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([O:15][CH2:16][CH2:17][N:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 12570310(4-Chlorodiphenyl)methyl beta-chloroethyl ether

Product 1

HCID 19370261HCID 19370261, compoundYield 73%

Procedure

Following a procedure similar to that described in Preparation 1, but using 2-[α-(4-chlorophenyl)benzyloxy]ethyl chloride and anhydrous piperazine, the title compound was obtained in a yield of 73%.

Workup

  1. customthat described in Preparation 1

Sources & evidence

ORD record
ord-065af5d8cdf5472ba07c39e40bd2fe3c
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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