Piperazine → HCID 19370344, compound

HRID 129732Notes

Reaction equation

HRID 129732 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([O:15][CH2:16][CH2:17]Cl)[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.[NH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([O:15][CH2:16][CH2:17][N:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 125703121-[(2-Chloroethoxy)(phenyl)methyl]-4-methylbenzene

Product 1

HCID 19370344HCID 19370344, compoundYield 65%

Procedure

Following a procedure similar to that described in Preparation 5(c), but using 2-[α-(4-methylphenyl)-benzyloxy]ethyl chloride and anhydrous piperazine, the title compound was obtained in a yield of 65%.

Sources & evidence

ORD record
ord-4645d29bfec142509c067e07b29c1024
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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