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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297412Generated: October 30, 2026

Skatole → 4-Chloro-1-methyl-1H-indole

https://huagongshe.com/reaction/1297412

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSkatoleHCID 6736—
Reactant4-ChloroindoleHCID 91345—
Product4-Chloro-1-methyl-1H-indoleHCID 13048759100%

Reaction Steps

According to the procedure of Preparation 13 (a), except substituting 4-chloroindole for the 3-methylindole, the title compound (2.2 g, 100%) was obtained as an amber oil: MS (ES) m/e 166.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250424B2
Source datasetuspto-grants-2007_07
ORD IDord-c438081b719b42a18b42cb7fb6d46354
Source noteuspto-grants-2007_07