反应详情

A solution of 1.07 g of pyridine-3-aldehyde and 1.21 g of D-cysteine in 60% v/v aqueous ethanol was heated under reflux for 4 hours. The mixture was cooled to room temperature and the resulting solid material was removed by filtration. The filtrate was concentrated by evaporation under reduced pressure, and 5 ml of ethanol were added to the resulting residue. Collecting the precipitated crystals by filtration gave 1.13 g (yield 54%) of the title compound, melting at 138°-139° C.

1. temperatureunder reflux for 4 hours
2. customthe resulting solid material was removed by filtration
3. concentrationThe filtrate was concentrated by evaporation under reduced pressure, and 5 ml of ethanol
4. additionwere added to the resulting residue
5. customCollecting the precipitated crystals
6. filtrationby filtration