Diisopropylethylamine → HCID 178516943, compound

HRID 1297639Notes

Reaction equation

HRID 1297639 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][NH2:10])[CH:5]=[CH:6][CH:7]=1.[S:11]1[CH2:17][C:15](=[O:16])[NH:14][C:12]1=S.CCN(C(C)C)C(C)C>>[F:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][NH:10][C:12]2[S:11][CH2:17][C:15](=[O:16])[N:14]=2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 5339282-(3-Fluorophenyl)ethanamineHCID 1201546Rhodanine

Product 1

HCID 178516943HCID 178516943, compound

Procedure

Similar procedure as described in example 1f was used, starting from 2-(3-fluoro-phenyl)-ethylamine, rhodanine (2-thioxo-thiazolin-4-one) and DIEA to give 2-[2-(3-fluoro-phenyl)-ethylamino]-thiazol-4-one. LC-MS m/e 239 (MH+).

Sources & evidence

ORD record
ord-97a3b6360ca14a4cbf43952a9486a91c
Source dataset
uspto-grants-2007_07
Patent number
US07250515B2

Reaction notes

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