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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297640Generated: October 30, 2026

6-Formyl-4-methoxy-3-(5-methyl-oxazol-2-yl)-quinoline → Piperidine

https://huagongshe.com/reaction/1297640

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Formyl-4-methoxy-3-(5-methyl-oxazol-2-yl)-quinolineHCID 58585861—
ReactantHCID 178516943HCID 178516943—
ProductPiperidineHCID 8082—
ProductHCID 178486803HCID 178486803—

Reaction Steps

Similar procedure as described in example 1g was used, starting from 6-formyl-4-methoxy-3-(5-methyl-oxazol-2-yl)-quinoline (example 16d), 2-[2-(3-fluoro-phenyl)-ethylamino]-thiazol-4-one (example 16e), benzolic and piperidine to give 2-[2-(3-Fluoro-phenyl)-ethylamino]-5-[1-[4-methoxy-3-(5-methyl-oxazol-2-yl)-quinolin-6-yl]-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 489 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250515B2
Source datasetuspto-grants-2007_07
ORD IDord-1ef368aaf67a4c80a2523cecb7441886
Source noteuspto-grants-2007_07