HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178466952, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2,2-Difluoro-2-pyridin-2-ylethaneamine | HCID 9964167 | — |
| Reactant | 4-Ethoxy-6-[2-methylsulfanyl-4-oxo-4h-thiazol-(5z)-ylidenemethyl]-quinoline-3-carbonitrile | HCID 58585820 | — |
| Product | HCID 178466952 | HCID 178466952 | — |
Reaction Steps
Similar procedure as described in example 14h was used, starting from 4-ethoxy-6-[2-methylsulfanyl-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-quinoline-3-carbonitrile (example 14g), 2,2-difluoro-2-pyridin-2-yl-ethylamine and DIEA to give 6-[2-(2,2-Difluoro-2-pyridin-2-yl-ethylamino)-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-ethoxy-quinoline-3-carbonitrile. LC-MS m/e 466 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-dde64e3c5aaf473d9aa342566cd2effc |
| Source note | uspto-grants-2007_07 |