HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 58585805, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Tert-butyl 4-hydroxypiperidine-1-carboxylate | HCID 643502 | — |
| Reactant | HCID 68824722 | HCID 68824722 | — |
| Product | HCID 58585805 | HCID 58585805 | — |
Reaction Steps
Similar procedure as described in example 28a was used, starting from 4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester, 6-iodo-quinoline-3-carbonitrile (example 14c) and sodium hydride to give 4-(3-cyano-6-iodo-quinolin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester. LC-MS m/e 480 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-065d33a6621945a6b6c5871cef514ce8 |
| Source note | uspto-grants-2007_07 |