HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Acetate → HCID 178452146, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 4-(3-Cyano-6-formyl-quinolin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester | HCID 58585840 | — |
| Reactant | HCID 178516935 | HCID 178516935 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178452146 | HCID 178452146 | — |
Reaction Steps
Similar procedure as described in example 28c was used, starting from 4-(3-cyano-6-formyl-quinolin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester (example 31b), 2-cyclopropylamino-thiazol-4-one, sodium acetate and acetic acid to give 4-{3-cyano-6-[2-cyclopropylamino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-quinolin-4-yloxy}-piperidine-1-carboxylic acid tert-butyl ester. LC-MS m/e 520 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-0ec74fb6fb0846759de427bc7b5e4ec8 |
| Source note | uspto-grants-2007_07 |