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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297666Generated: October 31, 2026

Sodium Acetate → HCID 11669484, compound

https://huagongshe.com/reaction/1297666

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium AcetateHCID 517045—
ReactantHCID 58585856HCID 58585856—
Reactant(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-oneHCID 137629131—
SolventAcetic AcidHCID 176—
ProductHCID 11669484HCID 11669484—

Reaction Steps

Similar procedure as described in example 38 was used, starting from 6-formyl-4-(2,2,2-trifluoro-1-trifluoromethyl-ethoxy)-quinoline-3-carbonitrile (example 45b), pseudothiohydantoin, sodium acetate and acetic acid to give 6-[2-amino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-(2,2,2-trifluoro-1-trifluoromethyl-ethoxy)-quinoline-3-carbonitrile. LC-MS m/e 447 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250515B2
Source datasetuspto-grants-2007_07
ORD IDord-cdc580d2a0b54daf959bee681aa6bbf6
Source noteuspto-grants-2007_07