Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzocaine | HCID 2337 | — |
| Reactant | 2-Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester | HCID 78943 | — |
| Product | HCID 68826262 | HCID 68826262 | — |
Reaction Steps
The mixture of ethyl 2-cyano-3-ethoxyacrylate (28.5 g, 0.168 mol) and 4-aminobenzoic acid ethyl ester (26.5 g, 0.16 mol) was heated at 150° C. for 2 h, detected by HPLC. After cooling to room temperature, the reaction mixture was dried under reduced pressure to give 4-(2-cyano-2-ethoxycarbonyl-vinylamino)-benzoic acid ethyl ester as a grey solid. LC-MS m/e 289 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07250515B2 |
|---|
| Source dataset | uspto-grants-2007_07 |
|---|
| ORD ID | ord-bf376c697fcd4541acc8b05a1a76e05a |
|---|
| Source note | uspto-grants-2007_07 |
|---|
