Hydrazine hydrate (1:1) → HCID 14500411, compound

HRID 129769Notes

Reaction equation

HRID 129769 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:28]2[CH:33]=[CH:32][C:31]([F:34])=[CH:30][CH:29]=2)=[C:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][N:17]3C(=O)C4=CC=CC=C4C3=O)[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.O.NN>>[NH2:17][CH2:16][CH2:15][N:12]1[CH2:13][CH2:14][C:9](=[C:8]([C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=2)[C:28]2[CH:33]=[CH:32][C:31]([F:34])=[CH:30][CH:29]=2)[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 19370379HCID 19370379, compound

Product 1

HCID 14500411HCID 14500411, compoundYield 97%

Procedure

The title compound was prepared in a yield of 97% in a similar manner to that described in Preparation 15 by reacting 4-[bis(4-fluorophenyl)methylene]-1-(2-phthalimidoethyl)piperidine and hydrazine hydrate.

Workup

  1. customdescribed in Preparation 15

Sources & evidence

ORD record
ord-9e64414a3f51456f9efe881a17905fb5
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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