Hydrochloric Acid → HCID 178458713, compound

Participants

Reaction Steps

To the solution of 6-[2-hydrazino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-isopropoxy-quinoline-3-carbonitrile (example 59, 15 mg, 0.042 mmol) in acetonitrile and water (8 mL), hydrochloride acid (1N, 0.17 mL) was added. The reaction completed by stirring the above mixture at room temperature for a short period of time. Then the solvents and excess hydrochloride acid were removed by vacuum and lyophilizer to give 6-[2-hydrazino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-isopropoxy-quinoline-3-carbonitrile hydrochloride salt. LC-MS m/e 354 (MH+).

Provenance & Evidence