Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Ethyl 3-ethoxy-2-(methanesulfonyl)prop-2-enoate | HCID 71353473 | — |
| Product | HCID 68825474 | HCID 68825474 | — |
Reaction Steps
The compound of 3-ethoxy-2-methanesulfonyl-acrylic acid ethyl ester (example 61c, 52 g, 0.234 mol) and aniline (38.65 g, 0.234 mol) was mixed and heated at 140-150° C. under stirring for two hours. After cooling the reaction to room temperature, solvent was removed to give 4-(2-ethoxycarbonyl-2-methanesulfonyl-vinylamino)-benzoic acid ethyl ester. The crude compound was used in the following reaction without further purification. LC-MS m/e 342 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07250515B2 |
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| Source dataset | uspto-grants-2007_07 |
|---|
| ORD ID | ord-7a1ad124355d4f0793ef0a5f6b3cf73a |
|---|
| Source note | uspto-grants-2007_07 |
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