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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 129770Generated: October 25, 2026

Hydrazine hydrate (1:1) → 1-(3-Aminopropyl)-4-[bis(4-fluorophenyl)-methylene]piperidine

https://huagongshe.com/reaction/129770

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
Reactant4-[Bis(4-fluorophenyl)methylene]-1-(3-phthalimidopropyl)piperidineHCID 19370302—
Product1-(3-Aminopropyl)-4-[bis(4-fluorophenyl)-methylene]piperidineHCID 1937032320%

Reaction Steps

The title compound was prepared in a yield of 20% in a similar manner to that described in Preparation 15' by reacting 4-[bis(4-fluorophenyl)methylene]-1-(3-phthalimidopropyl)piperidine (prepared as described in Preparation 48') and hydrazine hydrate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05470851
Source datasetuspto-grants-1995_11
ORD IDord-c1f28732367f4279bda2dbba8120ff17
Source noteuspto-grants-1995_11