HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-Amino-5-[1-(3-methanesulfonyl-4-phenyl-quinolin-6-yl)-meth-(z)-ylidene]-thiazol-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-(3-Methanesulfonyl-4-phenyl-quinolin-6-ylmethylene)-2-methylsulfanyl-thiazol-4-one | HCID 68825060 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Amino-5-[1-(3-methanesulfonyl-4-phenyl-quinolin-6-yl)-meth-(z)-ylidene]-thiazol-4-one | HCID 11531626 | — |
Reaction Steps
Similar procedure as described in example 41c was used, starting from 5-(3-methanesulfonyl-4-phenyl-quinolin-6-ylmethylene)-2-methylsulfanyl-thiazol-4-one (example 61k), and ammonia in methanol to give 2-amino-5-[1-(3-methanesulfonyl-4-phenyl-quinolin-6-yl)-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 410 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-1481e6bcc1e3490284c5c30bd1c43155 |
| Source note | uspto-grants-2007_07 |