Hydrazine hydrate (1:1) → HCID 19370383, compound

HRID 129771Notes

Reaction equation

HRID 129771 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]([N:14]2[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][N:22]3C(=O)C4=CC=CC=C4C3=O)[CH2:16][CH2:15]2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:2]=1.O.NN>>[NH2:22][CH2:21][CH2:20][N:17]1[CH2:16][CH2:15][N:14]([CH:7]([C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 19370296HCID 19370296, compound

Product 1

HCID 19370383HCID 19370383, compoundYield 98%

Procedure

The title compound was prepared in a yield of 98% in a similar manner to that described in Preparation 15' by reacting 4-[α-(3-pyridyl)benzyl]-1-(2-phthalimidoethyl)piperazine (prepared as described in Preparation 49') and hydrazine hydrate.

Workup

  1. customdescribed in Preparation 15'
  2. customprepared

Sources & evidence

ORD record
ord-0e0760761d7a4a83976cb7eb81872bfd
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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