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HRID1297714

反应详情

EQUATION

反应方程式

HRID 1297714 的结构方程式

REACTANTS

反应物

3
结构：CI
HCID6328

Methyl iodide

CH3I

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：N#Cc1cnc2ccc(C=C3SC(=S)NC3=O)cc2c1-c1cccnc1
HCID76823843

未命名化合物

PRODUCTS

生成物

1
结构：CSC1=NC(=O)C(=Cc2ccc3ncc(C#N)c(-c4cccnc4)c3c2)S1
HCID68824865

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

Similar procedure as described in example 41b was used, starting from 6-(4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-4-pyridin-3-yl-quinoline-3-carbonitrile (example 63d), iodomethane, and DIEA (diisopropylethylamine) in acetonitrile to give 6-(2-methylsulfanyl-4-oxo-4H-thiazol-5-ylidenemethyl)-4-pyridin-3-yl-quinoline-3-carbonitrile. LC-MS m/e 389 (MH+).