Hydrazine hydrate (1:1) → HCID 19370315, compound

HRID 129772Notes

Reaction equation

HRID 129772 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([N:14]2[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][N:22]3C(=O)C4=CC=CC=C4C3=O)[CH2:16][CH2:15]2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:3][CH:2]=1.O.NN>>[NH2:22][CH2:21][CH2:20][N:17]1[CH2:18][CH2:19][N:14]([CH:7]([C:4]2[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 19370352HCID 19370352, compound

Product 1

HCID 19370315HCID 19370315, compound

Procedure

The title compound was prepared in a quantitative yield in a similar manner to that described in Preparation 15' by reacting 4-[α-(4-pyridyl)benzyl]-1-(2-phthalimidoethyl)piperazine (prepared as described in Preparation 50') and hydrazine hydrate.

Workup

  1. customdescribed in Preparation 15'
  2. customprepared

Sources & evidence

ORD record
ord-c09bd1c7695e43e7823ce25b183f8c9f
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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