Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297722Generated: October 30, 2026

Neopentyl alcohol → HCID 58585841, compound

https://huagongshe.com/reaction/1297722

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNeopentyl alcoholHCID 6404—
ReactantPotassium hydrideHCID 82127—
Reactant4-Chloro-6-iodoquinoline-3-carbonitrileHCID 22466769—
SolventTetrahydrofuranHCID 8028—
ProductHCID 58585841HCID 58585841—

Reaction Steps

Similar procedure as described in example 28a was used, starting from 2,2-dimethyl-1-propanol, 4-chloro-6-iodo-quinoline-3-carbonitrile (example 14c) and potassium hydride in a solvent system of THF to give 4-(2,2-dimethyl-propoxy)-6-iodo-quinoline-3-carbonitrile. LC-MS m/e 367 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250515B2
Source datasetuspto-grants-2007_07
ORD IDord-a7db65f984ee4eae8de66e0df733369a
Source noteuspto-grants-2007_07