Hydrazine hydrate (1:1) → HCID 19370276, compound

HRID 129775Notes

Reaction equation

HRID 129775 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]([N:14]1[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][N:22]2C(=O)C3=CC=CC=C3C2=O)[CH2:16][CH2:15]1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.O.NN>>[NH2:22][CH2:21][CH2:20][N:17]1[CH2:16][CH2:15][N:14]([CH:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 19370353HCID 19370353, compound

Product 1

HCID 19370276HCID 19370276, compoundYield 52%

Procedure

The title compound was prepared in a yield of 52% in a similar manner to that described in Preparation 15' by reacting 4-[α-(2-pyridyl)benzyl]-1-(2-phthalimido-ethyl) piperazine (prepared as described in Preparation 53') and hydrazine hydrate.

Workup

  1. customdescribed in Preparation 15'
  2. customprepared

Sources & evidence

ORD record
ord-aacf264697de4b089701c4fa6617a5e2
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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