3-Pyridinecarboxaldehyde → HCID 18788450, compound

HRID 129811Notes

Reaction equation

HRID 129811 reaction equation
[CH:1]1[CH:6]=[N:5][CH:4]=[C:3]([CH:7]=O)[CH:2]=1.[C:9]([O:13][C:14]([NH:16][CH:17]([NH2:19])[CH3:18])=[O:15])([CH3:12])([CH3:11])[CH3:10]>C1(C)C=CC=CC=1>[N:5]1[CH:6]=[CH:1][CH:2]=[C:3]([CH2:7][NH:19][CH:17]([NH:16][C:14]([O:13][C:9]([CH3:10])([CH3:12])[CH3:11])=[O:15])[CH3:18])[CH:4]=1

Participants

4

Reactant 2

HCID 103713-PyridinecarboxaldehydeHCID 22323652HCID 22323652, compound

Product 1

HCID 18788450HCID 18788450, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2.92 g of 3-pyridyl carboxaldehyde are added to a solution of 4.82 g of N-(tert.butoxycarbonyl)ethanediamine in 50 ml of toluene in the presence of a dehydrating agent (4 Å molecular sieves) at about 5° C.

Sources & evidence

ORD record
ord-fe23d3969adf4ec3ba1d0af2901c2d74
Source dataset
uspto-grants-1995_11
Patent number
US05470855

Reaction notes

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