1,2-Ethanedithiol → HCID 131726112, compound

HRID 130302Notes

Reaction equation

HRID 130302 reaction equation
C(S)CS.[Br:5][CH2:6][CH2:7][C:8]([NH:10][C:11]1[CH:16]=[CH:15][C:14]([AsH2:17]=O)=[CH:13][CH:12]=1)=[O:9]>CO>[Br:5][CH2:6][CH2:7][C:8]([NH:10][C:11]1[CH:12]=[CH:13][C:14]([AsH2:17])=[CH:15][CH:16]=1)=[O:9]

Participants

4

Reactant 2

HCID 109021,2-EthanedithiolHCID 131726110HCID 131726110, compound

Product 1

HCID 131726112HCID 131726112, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1,2-Ethanedithiol (Aldrich; 25 μl, 0.30 mmol) was added to 4-(bromopropionamido)-phenylarsineoxide (Example 1.1; 100 mg, 0.30 mol) dissolved in 1 ml of hot methanol. After 5 min, a white solid precipitated and was collected. Yield: 63.7 mg, 0.16 mmol, 53%.

Workup

  1. customa white solid precipitated
  2. customwas collected

Sources & evidence

ORD record
ord-315f9db87ca84e2db37c536326e03a5f
Source dataset
uspto-grants-2008_06
Patent number
US07381572B2

Reaction notes

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