Hydrochloric Acid → HCID 69256214, compound

Participants

Reaction Conditions

Reaction Steps

Iron powder (5.03 g; 56 mmol), water (5 mL) and hydrochloric acid (0.1 mL; 36 mmol) are added consecutively to a solution of methyl 2-[4-(3-nitrophenoxy)phenyl]acetate (1.3 g; 4.5 mmol) in ethanol (20 mL). After stirring at 95° C. for four hours, the solid is filtered while still hot and the filtrate is stripped of solvent in vacuo to yield methyl 2-[4-(3-aminophenoxy)phenyl]acetate as an oil. Yield: 1.1 g (95%).

Provenance & Evidence