Thionyl Chloride → HCID 55207327, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of the product of Step 1 (430 mg, 2 mmol) in thionyl chloride (3 ml) and N,N-dimethylformide (2 drops) was heated at 70° C. for 3 hours. After cooling to room temperature the solvent was evaporated and the residue co-evaporated with toluene (×2) to give the title compound (D32) which was used directly in Step 1 of Example 272. 1H-NMR (CDCl3) δ 7.61 (1H, m), 8.25 (1H, m), 9.03 (1H, m).

Provenance & Evidence