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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 130494Generated: October 26, 2026

2-[6-(4-Iodo-phenyl)-7-oxo-3-trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[3,4-c]pyridin-1-yl]-5-methoxy-N-pyridin-3-yl-benzamide → HCID 58630250, compound

https://huagongshe.com/reaction/130494

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[6-(4-Iodo-phenyl)-7-oxo-3-trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[3,4-c]pyridin-1-yl]-5-methoxy-N-pyridin-3-yl-benzamideHCID 58630234—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 58630250HCID 5863025095%

Reaction Steps

2-[6-(4-Iodo-phenyl)-7-oxo-3-trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[3,4-c]pyridin-1-yl]-5-methoxy-N-pyridin-3-yl-benzamide (15 mg, 0.023 mmol) was combined with 5% palladium on carbon and stirred in ethanol under 1 atmosphere of hydrogen for 12 h. The reaction mixture was filtered through diatomaceous earth and the solvent evaporated to give the title compound (11 mg, 95%) as a colorless solid. MS (ES+) 508.0 (M+H)+(100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07381732B2
Source datasetuspto-grants-2008_06
ORD IDord-24386bfe1d524752912c398204db8879
Source noteuspto-grants-2008_06