HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2RS,3RS)-3-amino-1-phenoxy-butan-2-ol → (2RS,3RS)-3-[1-(4-fluorophenyl)indazol-5-yl]oxy-4-phenoxy-butan-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2RS,3RS)-3-amino-1-phenoxy-butan-2-ol | HCID 15105310 | — |
| Reactant | 1-(4-fluorophenyl)-5-iodo-1H-indazole | HCID 59251128 | — |
| Product | (2RS,3RS)-3-[1-(4-fluorophenyl)indazol-5-yl]oxy-4-phenoxy-butan-2-amine | HCID 66812100 | — |
Reaction Steps
Prepared as described in Example 1 from (2RS,3SR)-3-amino-1-phenoxy-butan-2-ol (319 mg, 1.75 mmol), and 1-(4-fluorophenyl)-5-iodoindazole (710 mg, 2.10 mmol). Yield 244 mg (36%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728030B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-b4d9d8e75f5e40e998bb31e81d1abe76 |
| Source note | uspto-grants-2010_06 |