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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131486Generated: November 1, 2026

(S)-2-(2-ethoxyethyl)piperazine → (S)-10-[3-(2-Ethoxyethyl)-piperazin-1-yl]-2-methyl-4H-3-thia-1,4,9-triazabenzo[f]azulene

https://huagongshe.com/reaction/131486

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(2-ethoxyethyl)piperazineHCID 45099473—
Reactant2-methyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamineHCID 135797744—
Product(S)-10-[3-(2-Ethoxyethyl)-piperazin-1-yl]-2-methyl-4H-3-thia-1,4,9-triazabenzo[f]azuleneHCID 135525285—

Reaction Steps

In a manner similar to that described in Example 300, combine 2-methyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamine (0.534 g, 2.01 mmol) and (S)-2-(2-ethoxyethyl)piperazine (0.635 g, 4.01 mmol) to obtain the title compound: Exact Mass, Calc: 372.1858; Found: 372.1867.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384934B2
Source datasetuspto-grants-2008_06
ORD IDord-4547b28dff204ed9bc849e2235959cfa
Source noteuspto-grants-2008_06