HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(Piperazin-2-yl)ethanol → (S)-2-[4-(2-Isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-yl)-piperazin-2-yl]ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(Piperazin-2-yl)ethanol | HCID 1519380 | — |
| Reactant | 2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamine hydrochloride | HCID 135797741 | — |
| Product | (S)-2-[4-(2-Isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-yl)-piperazin-2-yl]ethanol | HCID 135543671 | — |
Reaction Steps
In a manner such as that described in Example 300, combine 2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamine hydrochloride (0.558 g, 1.89 mmol) and (S)-2-piperazin-2-yl-ethanol (0.493 g, 3.79 mmol) to obtain the title compound: mass spectrum (APCI): m/z=372.4 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07384934B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-be7519a5d7ad4aed8eb136ef194b0feb |
| Source note | uspto-grants-2008_06 |