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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131490Generated: October 31, 2026

(S)-2-(2-ethoxyethyl)piperazine → (S)-10-[3-(2-Ethoxyethyl)-piperazin-1-yl]-2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene

https://huagongshe.com/reaction/131490

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(2-ethoxyethyl)piperazineHCID 45099473—
Reactant2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamine hydrochlorideHCID 135797741—
Product(S)-10-[3-(2-Ethoxyethyl)-piperazin-1-yl]-2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azuleneHCID 135430661—

Reaction Steps

In a manner similar to that described in Example 300, combine 2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamine hydrochloride (0.523 g, 1.77 mmol) and (S)-2-(2-ethoxyethyl)piperazine (0.561 g, 3.54 mmol) to obtain the title compound: mass spectrum (APCI): m/z =400.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384934B2
Source datasetuspto-grants-2008_06
ORD IDord-99406570a9b5441fb5a4be15a95427f0
Source noteuspto-grants-2008_06