HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(2-ethoxyethyl)piperazine → (S)-10-[3-(2-Ethoxyethyl)-piperazin-1-yl]-2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(2-ethoxyethyl)piperazine | HCID 45099473 | — |
| Reactant | 2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamine hydrochloride | HCID 135797741 | — |
| Product | (S)-10-[3-(2-Ethoxyethyl)-piperazin-1-yl]-2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene | HCID 135430661 | — |
Reaction Steps
In a manner similar to that described in Example 300, combine 2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene-10-ylamine hydrochloride (0.523 g, 1.77 mmol) and (S)-2-(2-ethoxyethyl)piperazine (0.561 g, 3.54 mmol) to obtain the title compound: mass spectrum (APCI): m/z =400.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07384934B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-99406570a9b5441fb5a4be15a95427f0 |
| Source note | uspto-grants-2008_06 |