2-Methyl-5,10-dihydro-4H-thieno[2,3-b][1,5]benzodiazepine-4-thione → (S)-2-Methyl-1-[4-(2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulen-10-yl)piperazin-2-yl]-propan-2-ol

Participants

Reaction Steps

In a manner similar to that described in Example 359, combine 2-methyl-4,9-dihydro-3-thia-4,9-diazabenzo[f]azulene-10-thione (0.574 g, 2.33 mmol) and (S)-2-methyl-1-piperazin-2-yl-propan-2-ol (0.369 g, 2.33 mmol) to obtain the title compound: mass spectrum (APCI): m/z=371.2 (M+1).

Provenance & Evidence