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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131666Generated: October 25, 2026

3-[(Dimethylamino)methyl]-4-methoxyaniline → N-[3-(Dimethylaminomethyl)-4-methoxyphenyl]-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1'-biphenyl-4-carboxamide

https://huagongshe.com/reaction/131666

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(Dimethylamino)methyl]-4-methoxyanilineHCID 13397096—
Reactant2'-Methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1'-biphenyl-4-carbonyl chlorideHCID 21078801—
ProductN-[3-(Dimethylaminomethyl)-4-methoxyphenyl]-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1'-biphenyl-4-carboxamideHCID 10276091—

Reaction Steps

N-[3-(Dimethylaminomethyl)-4-methoxyphenyl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carbonyl chloride and 3-(dimethylaminomethyl)-4-methoxyaniline using method K. LCMS; retention time 2.65 min, MH+ 457.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384963B2
Source datasetuspto-grants-2008_06
ORD IDord-a72dfca095be4c3291728f7d44994a9c
Source noteuspto-grants-2008_06