HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178418361, compound → HCID 178509666, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Reactant | HCID 178509667 | HCID 178509667 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178509666 | HCID 178509666 | 181.2% |
Reaction Steps
N-(2-Aminomethylphenyl)methylsulphonamide N-(2-Cyanophenyl)methylsulphonamide (1.0 g) and raney nickel in ethanol/0.880 ammonia (100 ml, 1:1) were hydrogenated under 64 Atm. of hydrogen at room temperature for 27 h. The reaction was filtered through celite and the solvent evaporated under vacuum to give N-(2-aminomethylphenyl)methylsulphonamide (915 mg, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07384963B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-b0a6b3fbc4084a0b8902d866d55477f7 |
| Source note | uspto-grants-2008_06 |