Bromomethylcyclopropane → HCID 10205516, compound

HRID 131695Notes

Reaction equation

[Cl:1][C:2]1[CH:30]=[CH:29][C:5]([CH2:6][NH:7][C:8]([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[C:20]([C:22]4[O:23][C:24]([CH3:27])=[N:25][N:26]=4)[CH:19]=[CH:18][C:17]=3[CH3:28])=[CH:12][CH:11]=2)=[O:9])=[CH:4][CH:3]=1.[CH:31]1([CH2:34]Br)[CH2:33][CH2:32]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]([CH2:34][CH:31]2[CH2:33][CH2:32]2)[C:8]([C:10]2[CH:11]=[CH:12][C:13]([C:16]3[CH:21]=[C:20]([C:22]4[O:23][C:24]([CH3:27])=[N:25][N:26]=4)[CH:19]=[CH:18][C:17]=3[CH3:28])=[CH:14][CH:15]=2)=[O:9])=[CH:29][CH:30]=1

Participants

Reactant 2

HCID 81503Bromomethylcyclopropane

HCID 10295475HCID 10295475, compound

Product 1

HCID 10205516HCID 10205516, compound

Procedure

N-(4-Chlorobenzyl)-N-(cyclopropylmethyl)-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from N-(4-chlorobenzyl)-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide and cyclopropylmethyl-bromide using method L. LCMS; retention time 3.89 min, MH+ 472/474.

Sources & evidence

ORD record: ord-1f5b1816929642318d2a0e58952047aa
Source dataset: uspto-grants-2008_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07384963B2

Reaction notes

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