Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131707Generated: October 31, 2026

2-(Trifluoromethyl)benzylamine → HCID 10114893, compound

https://huagongshe.com/reaction/131707

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic AcidHCID 11220119—
ProductHCID 10114893HCID 10114893—

Reaction Steps

2′-Methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-trifluoromethylbenzyl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 2-trifluoromethylbenzylamine using method N. NMR; δH [2H6]—DMSO 9.23,(1H, t), 8.04,(2H, d), 7.91,(1H, dd), 7.78,(1H, d), 7.75,(1H, d), 7.67,(1H, t), 7.56,(4H, m), 7.49,(1H, t), 4.70,(2H, d), 2.57,(3H, s),2.33,(3H, s). LCMS; retention time 3.58 min, MH+ 452.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384963B2
Source datasetuspto-grants-2008_06
ORD IDord-3bd0a7a561894adb922ce4bac7e4ee42
Source noteuspto-grants-2008_06