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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131708Generated: October 30, 2026

3-(Trifluoromethyl)benzylamine → HCID 10275729, compound

https://huagongshe.com/reaction/131708

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzylamineHCID 75962—
Reactant4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoic AcidHCID 11220119—
ProductHCID 10275729HCID 10275729—

Reaction Steps

2′-Methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(3-trifluoromethylbenzyl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 3-trifluoromethylbenzylamine using method N. NMR; δH [2H6]—DMSO 9.24,(1H, t), 8.00,(2H, d), 7.90,(1H, dd), 7.77,(1H, d), 7.69-7.52,(7H, m), 4.59,(2H, d), 2.56,(3H, s), 2.31,(3H, s). LCMS; retention time 3.59 min, MH+ 452.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384963B2
Source datasetuspto-grants-2008_06
ORD IDord-8c3b322e85d840f78afcae8dd9fc2379
Source noteuspto-grants-2008_06